Nippon Shokakibyo Gakkai Zasshi
Online ISSN : 1349-7693
Print ISSN : 0446-6586
Case report
A case of double cancer of the liver, cholangiocarcinoma and hepatocellular carcinoma detected in a patient with hepatitis C 13 years after diminution of HCV-RNA by interferon treatment
Takako TSUMURAShintaro TAKAKIHiroshi AIKATAYuki KIMURAYoshio KATAMURATakahiro AZAKAMITomokazu KAWAOKAMasataka TSUGEHiromi SANETOUKoji WAKIAkira HIRAMATSUMichio IMAMURAYoshiiku KAWAKAMIShoichi TAKAHASHIKoji ARIHIROKazuaki CHAYAMA
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2009 Volume 106 Issue 5 Pages 674-683

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Abstract

A 56 year-old man with chronic hepatitis C (HCV) was treated with interferon therapy and achieved sustained virological response (SVR) in 1993. Thirteen years later, in 2006 two liver tumors, 35-mm and 11-mm in diameter respectively, were detected in liver segment 6. Hepatic resection was performed, and pathologically one nodule was diagnosed as cholangiocellular carcinoma (CCC) and the other hepatocellular carcinoma (HCC). Continuity was not recognized between these tumors, thus, we diagnosed this case as double cancer (CCC and HCC). Here, we report a rare case of double cancer (CCC and HCC) that developed 13 years after achieving SVR for HCV infection.

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© 2009 by The Japanese Society of Gastroenterology
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