Abstract
1) The comparative survey of the pre-operative gastric analysis and the histonatholozicfinding of the resected stomach was performed in 134 patients.
2) On the histopathologic study the inflammatory process of the gastric mucosa associatedwith cancer was diffusely distributed but one associated with peptic ulcer wasmarkedly localized in the pyloric portion,
3) The gastric analysis was carried out with subcutaneous injection of 0.02mgm perkg. and 0.1 mgm per kg. of histamine and with Ka tsch-Kalk test meal.
4) The pathologic change of the gastric mucosa in the fundus as well as pyloricportion was classified into three grades, according to the degree of atrophy of thegastric proper gland. “gastritis form” was based upon the combination of thechanges of the fundus and the pyloric portion.
5) The amount of secretion of Hcl and gastric juice for 60 min. following the subcutaneousinjection of 0.02 mgm per kg. or 0.1 mgm per kg. of histamine was on intimaterelation with the pathologic change of mucosa of the fundus.
6) There was a close correlation between the maximum free Hcl acidity on Katsch-Kalk test meal and “gastritis form”.
7) The pathologic change of mucosa of the fundus and the number of the parietalcells were correlated each other.The more atrophic change of mucosa of the fundus, the less number of theparietal cells.
8) The gastric acidity and the amount of Hcl was correlated with the number of theparietal cells.
9) Hyperacidity was encountered in 63.2% of the stomach with marked hematemesisand/or melena.
Such stomach was histologically characterized by the prominent scar-formationaround the ulcer, but was not correlated with the location or the number of theulcer.
