Abstract
Serum ACE activity was measured for a variety of liver diseases, and was found to be elevated in patients with acute hepatitis, chronic hepatitis and liver cirrhosis.
The elevation of ACE activity was recognized in both compensated and decompensated liver cirrhosis, and there is no relationship between the ACE activity and arterial oxygen pressure in these cases.
On the other hand, patients with fatty liver had normal ACE activity, and patients with obstructive jaundice revealed activity slightly lower than that of the controls.
This may suggest that the elevation of ACE activity indicates the degree of liver cell damage, and thus serum ACE determination is useful in diagnosing liver diseases under certain conditions.