Special Issue on Recent Progress in Nonlinear Theory and Its Applications
Noise reduction and signal enhancement by receptor synchronization
2020 Volume 11 Issue 4 Pages 601-609
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2020 Volume 11 Issue 4 Pages 601-609
The ligand-receptor interaction is critical for signal transduction in biological systems. The binding interaction between a receptor and its cognate ligand has been extensively investigated at the molecular level. However, there are often many non-ligand molecules surrounding receptors, and it is very likely that they function as extraneous noise that disrupts authentic signal transduction. Herein we demonstrated that excitable receptor synchronization during signal transduction is key for noise reduction and signal enhancement.
