Two Cases of Acute Interstitial Pneumonia with Different Patterns of Radiologic Findings at Disease Onset

Abstract

Acute interstitial pneumonia (AIP) is a rapidly progressive lung disease that is clinically characterized as acute lung injury. Chest radiographs and computed tomography of AIP reveal diffuse or patchy infiltrates in bilateral lung fields. Case 1 exhibited bilateral ground-glass opacities at the onset. Case 2 exhibited patchy air space consolidations in the bilateral lung fields. Both cases died due to progressive respiratory failure, and their pathologic findings revealed diffuse alveolar damage (DAD) pattern. In particular, case 2 exhibited the histological features of acute and organizing phase of DAD that indicated disease progression.