A Clinical and Histological Analysis of Extramammary Paget’s disease at Itabashi Hospital, Nihon University School of Medicine

Abstract

We analyzed the clinical and histological characteristics of 20 patients with extramammary Paget’s disease at Itabashi Hospital, Nihon University School of Medicine. Two out of 20 patients came to the hospital at an advanced stage (Stage III-IV) of disease. There is significant need for improvement of the diagnostic ability, and the patients need to understand the disease to recognize and initiate treatment as early as possible. Immunohistochemical staining of cytokeratin (CK) 7 and CK20 is useful in the diagnosis of the disease.