2010 Volume 69 Issue 4 Pages 238-242
To establish a prognostic evaluation system and treatment strategy for lung cancer metastases to the bones, we evaluated the prognosis-related factors and the effects of the zoledronic acid hydrate on bone metastases in 93 patients. Consequently, in this retrospective study of 30 patients, the performance status (PS), paralysis, and total scores of the scoring system for the preoperative evaluation of metastatic spine tumor prognosis (Tokuhashi score) significantly affected the survival periods. In the prospective study of 63 patients, there were significant differences between the PS and visual analogue scale (VAS) within a 6-month period. Only PS significantly affected the prognosis in Cox regression analyses. There was less than 10/100 VAS after treatment in 64.7% of patients after administration of zoledronic acid hydrate.
