Abstract
A 72-year-old man with chronic renal failure who was undergoing hemodialysis was admitted to our hospital because of anemia. Gastrointestinal fiberscopy showed a type 2 tumor in the middle part of the greater curvature of the stomach, and histopathological analysis of the tumor biopsy revealed adenocarcinoma. Distal gastrectomy was performed with lymph node dissection. On the basis of the histopathological examination, the tumor was an adenocarcinoma with lymphoid stroma (por2) and EBV was detected in tumor cells with in situ hybridization for EBV-encoding small RNAs. Therefore, the tumor was diagnosed as EBV-associated gastric carcinoma. The present case demonstrated that EBV-associated with gastric carcinoma might develop because of depression of cellular immunity in chronic renal failure.
