Relation Between Chemotherapy Toxicity and Serum Albumin Levels During Chemotherapy for 7 Cases of Inoperable Gastric Cancer

Abstract

Patients undergoing chemotherapy for advanced and recurrent gastric cancer tend to worsen their nutrition due to chemotherapy toxicity. We examined the relationship between serum albumin levels, weight loss and chemotherapy toxicity in 7 cases that were treated with S-1 and Cisplatin. We recognized that the grade of hematological toxicity tended to be higher in proportion to weight loss of more than 3 kg. In general, the nutritional status of patients can influence the efficacy and safety of anti-cancer drugs and continuation of chemotherapy. Therefore these findings suggest that active nutritional management can allow for the continuation of chemotherapy, thus supporting the patientÅfs quality of life.