Journal of Nihon University Medical Association
Online ISSN : 1884-0779
Print ISSN : 0029-0424
ISSN-L : 0029-0424
Special Articles: Trend of the Cardiovascular Drugs 3
Statin
Takafumi Hiro
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Keywords: statin, LDL-cholesterol, ischemic heart disease, rhabdomyolysis
JOURNAL FREE ACCESS

2014 Volume 73 Issue 2 Pages 81-84

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Abstract

Statins, inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase, attenuate the biosynthesis of cholesterol to increase the number of LDL-cholesterol (LDL-C) receptors, and consequently decrease serum LDL-C levels. Statins represent one of the key medication classes for both primary and secondary prevention of ischemic heart disease.

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© 2014 The Nihon University Medical Association
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