Abstract
In recent years, assisted reproductive technology (ART) has developed remarkably, and many infertile couples can now have babies using these approaches. In addition to ART, cancer therapies have also developed and survival rates have improved greatly. Cancer therapies may be harmful to spermatogenesis. Recently, cryopreservation of sperm has been recommended for men of reproductive age with malignancies before undergoing cancer treatment. Thus, we attempted to perform in vitro fertilization (IVF) using cryopreserved sperm for the purpose of future preservation of fertility of cancer-bearing male patients at Nihon University Itabashi Hospital. We report two cases of sperm cryopreservation. Neither case could provide prepare fresh sperm on the day of oocyte retrieval due to work commitments away from their partner. Sperm cryopreservation was performed with the slow-freezing method. Both cases obtained multiple good embryos and blastocysts and led to pregnancies. The technique of cryopreserved sperm is also available in Nihon University Itabashi Hospital. However it is necessary to cooperate with oncologists or the physician in charge when fertility preservation technologies are performed for patients with malignancies.
