Abstract
Periodontitis is one of the most common chronic infectious disorders associated with anaerobic subgingival microflora. Host immune responses and lifestyle determine the extent and severity of periodontitis. Recently, many epidemiological studies have revealed that periodontitis affects systemic diseases, such as aspiration pneumonia, diabetes mellitus, arteriosclerosis, and pregnancy complications. In this review, we address the relationships between periodontitis and systemic diseases.