Journal of Nihon University Medical Association
Online ISSN : 1884-0779
Print ISSN : 0029-0424
ISSN-L : 0029-0424
Reserch Reports:
The Clinical Characteristics of Six Cases with Late-Onset Group B Streptococcal Meningitis
Takeaki TamuraWakako IshiiSonoko KubotaKaori KimuraEmiko MomokiYuki KawamuraAyumi FukudaYukihiko FujitaTatsuo FuchigamiShori Takahashi
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JOURNAL FREE ACCESS

2017 Volume 76 Issue 2 Pages 74-78

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Abstract

Group B streptococcus (GBS) is a causative pathogen of meningitis and sepsis in neonates and early infants. To describe the characteristics of GBS meningitis in children, we studied 6 patients that were treated at the Department of Pediatrics and Child Health, Nihon University Itabashi Hospital. Among them, five were late onset cases and one was ultra-late onset. We determined the risk factors for neurological sequelae to be: a long period of initial symptoms before admission, septic shock at admission, the use of artificial ventilation, intractable seizure and a long serum CRP-positive period. There was no correlation between the capsular types and severity. Two cases had adverse outcomes and revealed strains that were less susceptible to ampicillin. Reconsideration is necessary to provide preventive measures against GBS in medical institutes.

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© 2017 The Nihon University Medical Association
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