Invasive Thymoma Accompanied by Central Necrosis and Venous Invasion

Abstract

Herein, we report a rare case of an invasive thymoma accompanied by central necrosis and venous invasion in a 76-year-old female patient. The tumor was resected with partial resection of the left upper lobe of the lung. Histopathological findings showed central necrosis surrounded by a well-circumscribed tumor nest of type AB thymoma. The Classification of Malignant Tumours (TNM) stage of the tumor was T1aN0M0 stage I. Elastica van Gieson’s staining showed venous invasion of the thymoma. Further investigation is necessary, because this type of growth is rare and the pathological significance for invasive thymoma remains unclear.