A Case of Aggressive Squamous Cell Carcinoma of the Breast with a Poor Prognosis

Abstract

We report a case of squamous cell carcinoma of the breast that was treated with paclitaxel and bevacizumab. After a 70-year-old woman noticed a lump in the left breast, she came to our hospital, and was diagnosed with squamous cell carcinoma of the left breast and liver metastasis. She achieved a partial response to Paclitaxel and Bevacizumab therapy, but after two courses, she was admitted for transient ischemic attack (TIA). Upon hospitalization, interstitial pneumonitis without any symptoms was found. We subsequently changed the treatment to S-1 therapy. However, the liver metastasis spread immediately. She died 9 months after first visiting our hospital. Squamous cell carcinoma of the breast is rare and generally aggressive. While the same chemotherapy as invasive ductal carcinoma is often selected, the outcomes are not good. We hope to select the most effective treatment strategy for squamous cell carcinoma of the breast.