Journal of Nihon University Medical Association
Online ISSN : 1884-0779
Print ISSN : 0029-0424
ISSN-L : 0029-0424
Special Articles:
Treatable Dementia: Thiamine Deficiency
Takahiro Suzuki
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2018 Volume 77 Issue 5 Pages 309-312

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Abstract
Nutritional deficiencies are not uncommon. Therefore, we must understand whether nutritional deficiencies can cause cognitive disorder. Wernicke-Korsakoff encephalopathy (WKE), which occurs as a result of thiamine deficiency, pellagra due to nicotinic acid deficiency, malignant anemia, which occurs as a result of vitamin B12 deficiency, and diabetic coma due to hypoglycemia, can all lead to cognitive disorder. We must treat these disorders at the appropriate time, in order to prevent the cognitive disorder from becoming chronic. In this article, we consider WKE. WKE is a metabolic disease that is treatable, when diagnosed in the early stage. In the general setting, it is difficult to diagnose WKE appropriately. Therefore, we must determine whether this nutrition deficiency can contribute to the development of this treatable cognitive disorder.
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