Abstract
We present multicentric glioblastomas radiologically mimicking metastatic tumors. A 57-year-old female
presented with multiple brain masses accompanied by generalized seizures. Since there was no primary lesion
considered to be the origin, the patient underwent craniotomy to remove the mass. The mass was pathologically
diagnosed as glioblastoma, IDH-wildtype. When we found a multicentric tumor mass in the brain, a metastatic
tumor was first suspected, and radiotherapy without surgical resection was believed to be acceptable. However,
glioblastoma, which requires intensive chemoradiotherapy, rarely demonstrates multiple lesions as in the presented case. Therefore, surgical resection should be considered to make a diagnosis and treat multiple brain tumors,
especially in cases with no certain primary lesion.
