Longitudinal MR spectroscopy in two patients with clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS)

Abstract

  We performed MR spectroscopy of the splenium of the corpus callosum in two patients with clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS). MRS in the acute stage showed a high choline/creatine ratio in comparison with that in the chronic stage with complete clinical and radiological recovery, which suggested myelin dysfunction of the myelin, including intramyelinic edema.