A severe case of acute flaccid myelitis with confirmed various antiglycolipid antibodies including anti-GM1 antibody in the acute phase

Abstract

  Anti-glycolipid antibodies have been confirmed in approximately 50% of acute flaccid myelitis (AFM) cases and approximately 60% of GBS cases. Furthermore, in GBS, the type of anti-glycolipid antibody is associated with clinical disease type. We experienced an AFM case with multiple anti-glycolipid antibodies including confirmed anti-GM1 antibody. Although there has been no report of anti-GM1 antibody-positive AFM, the clinical findings in this case are similar to that of anti-GM1 antibody-positive GBS. This case is considered important for studying the significance of anti-glycolipid antibody in AFM and its difference from other flaccid paralysis disorders such as GBS.