2021 Volume 53 Issue 6 Pages 425-429
Anti-N-Methyl-d-aspartate (NMDA) receptor encephalitis was identified approximately 13 years ago. Previous studies have shown that anti-NMDA receptor encephalitis is the most common auto-antibody-mediated encephalitis. It is necessary to consider the differential diagnosis in cases of acute-onset psychotic symptoms and involuntary movements. The elucidation of pathological conditions and diagnosis/treatment policies has made great progress. However, without proper treatment, patients need a very long time to recover, sequelae may remain, or death may occur in the acute phase. Early diagnosis and treatment are very important. This review provides an overview of anti-NMDA receptor encephalitis, the characteristics of pediatric cases, and the recently proposed approach for early diagnosis and treatment.
