Abstract
We reported an 11-year-old boy with multiple sclerosis who relapsed whenever he suffered from upper respiratory infection. He gained transient remission with peroral steroid therapy for 6 months after his initial onset. But, since his first relapse, he was unable to support his posture for 20 months because of his severe trunk ataxia. During that period, he was treated with a high-dose of methylprednisolone (pulse therapy) in exacerbation and gained remission. Subsequently, even though he had not neurological disorders, we treated him with pulse therapy, whenever he seemed to be in aggravation with high levels of CSF IgG and myelin basic protein (MBP). Then he maintained remission and became quite normal. A pulse therapy according to the CSF findings was beneficial in the management for acute multiple sclerosis relapse.
