Abstract
On the basis of experiences of chromosome aberrations and some established embryopathy, the association of several minor structural anomalies may indicate an disorder of organogenesis. However, the fact that some structural abnormalities occur as a result of neurological disturbance should be kept in mind. In some of structural anomalies, the significance as an aid of suggesting embryopathy may be varied by age and genetic background of the patients, or criteria of the examiners. Then, one should be careful and experienced enough to check the structural anomalies of prenatal origin in order to avoid a risk of over-diagnosis.
