Focal Brain Lesion Accompanied by Exanthem Subitum: Report of Two Cases

Abstract

We report two cases with exanthem subitum in which hemiparesis developed during the acute infectious phase. Magnetic resonance imaging (MRI) demonstrated a cerebral ischemic infarct in the territory of the right lenticulostriate artery in one patient. Along the right temporal and parieto-occipital cortex of the other patient, there were high-signal-intensity lesions on T₂-weighted images, which showed marked enhancement by gadolinium on T₁ weighted images. These findings suggested that the brain lesions were caused by vasculopathy that accompanied human herpes virus-6 infection.