NO TO HATTATSU
Online ISSN : 1884-7668
Print ISSN : 0029-0831
ISSN-L : 0029-0831
GM1-Gangliosidosis Knockout Mouse
Akihiro Oshima
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JOURNAL FREE ACCESS

1998 Volume 30 Issue 2 Pages 148-151

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Abstract
We generated a β-galactosidosis mouse by gene targeting in an embryonic stem cell. Clinical, pathological, and biochemical analyses revealed that this mouse is a useful animal model to study the pathogenesis and therapy of human GM1-gangliosidosis.
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© Japanese Society of Child Neurology
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