Effects of MeIQx and EGF Applications on the Hamster Tongue after Excisional Wounding

Naohiro Ito; Motohisa Kamiya; Hisanori Kato; Emiko Sato; Seiichi Konishi; Hironori Tanaka; Hatsuhiko Maeda; Yoichiro Kameyama

doi:10.3353/omp.1.29

Original

Effects of MeIQx and EGF Applications on the Hamster Tongue after Excisional Wounding

Naohiro Ito, Motohisa Kamiya, Hisanori Kato, Emiko Sato, Seiichi Konishi, Hironori Tanaka, Hatsuhiko Maeda, Yoichiro Kameyama

Author information

Naohiro Ito
Department of Pathology, School of Dentistry, Aichi-Gakuin University, Nagoya
Motohisa Kamiya
Department of Pathology, School of Dentistry, Aichi-Gakuin University, Nagoya
Hisanori Kato
Department of Pathology, School of Dentistry, Aichi-Gakuin University, Nagoya
Emiko Sato
Department of Pathology, School of Dentistry, Aichi-Gakuin University, Nagoya
Seiichi Konishi
Department of Pathology, School of Dentistry, Aichi-Gakuin University, Nagoya
Hironori Tanaka
Department of Pathology, School of Dentistry, Aichi-Gakuin University, Nagoya
Hatsuhiko Maeda
Department of Pathology, School of Dentistry, Aichi-Gakuin University, Nagoya
Yoichiro Kameyama
Department of Pathology, School of Dentistry, Aichi-Gakuin University, Nagoya

Keywords: hamster tongue, excisional wounding, MeIQx, EGF

JOURNAL FREE ACCESS

1996 Volume 1 Issue 1 Pages 29-32

DOI https://doi.org/10.3353/omp.1.29

Details

Abstract

The effects of MeIQx and EGF applications on the tongues of hamsters after excisional wounding were investigated histologically. The tongues of the control animals which received applications of distilled water after excisional wounding showed only a hyperkera-tinized epithelium. In contrast, the tongues of the animals which received applications of MeIQx after excisional wounding exhibited epithelial dysplasia. The tongues of the animals which received applications of EGF after excisional wounding displayed a hyperparakera-tinized epithelium without epithelial dysplasia. The tongues of the animals which received applications of both MeIQx and EGF together after excisional wounding showed a hyperkera-tinized epithelium similar to those of the controls.

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