Oral Medicine & Pathology
Online ISSN : 1882-1537
Print ISSN : 1342-0984
ISSN-L : 1342-0984
Review
Significance of podoplanin expression in normal and pathological conditions of the oral and maxillofacial regions
Yuji MiyazakiHarumi InouePatricia González-AlvaKentaro KikuchiMasahiro FujinamiHozumi TsuchiyaYoshihiro NoguchiNoriaki YoshidaFumio IdeKaoru Kusama
Author information
JOURNAL FREE ACCESS

2011 Volume 16 Issue 1+2 Pages 3-8

Details
Abstract
Podoplanin, a transmembrane glycoprotein that was originally detected in puromycin-induced nephrosis on the surface of rat podocytes, is expressed specifically by lymphatic endothelium. Recent studies have shown that the protein is expressed in a variety of normal as well as neoplastic tissues, and that its expression might be related to cell migration and invasion. In this review, we describe the expression and function of podoplanin under normal as well as pathological conditions of the oral and maxillofacial regions, and we discuss its significance.
Content from these authors
© 2011 The Japanese Society of Oral Pathology
Previous article Next article
feedback
Top