Metastatic Prostate Carcinoma to the Mandible: Report of a case

Abstract

We report a case of metastatic prostate carcinoma to the mandible. A 76-year-old male was referred to our hospital due to a complaint of swelling in the left mandible. Roentgenographic findings revealed a radiolucent lesion in the angle of mandible, but scintigraphy did not reveal a specific accumulation in the body except in the mandible. A diagnosis of metastatic prostate carcinoma to the mandible was made through the biopsy specimens from the mandible and from urological examinations. Orchidectomy was performed after the administration of LH-RH agonist and anti-androgenic agent. Elevated blood levels of prostatic specific antigen and γ-seminoprotein were markedly decreased. Furthermore, these therapies were extremely effective not only to the primary lesion but also to the metastatic lesion in the mandible.