Epithelial Myoepithelial Carcinoma of the Salivary Gland: A case report with immunohistochemical examination and threedimensional imaging

Abstract

A 70 year-old man noticed a mass gradually enlarging in the left parotid gland region three months before consulting our hospital. Histopathologically, the tumor consisted of two patterns of cellular growth, involving ductal cells in the inner and clear cells in the outer layers. From the microscopic and immunohistochemical findings, the tumor was diagnosed as an epithelial myoepithelial carcinoma. Confocal laser microscopy further suggested that the clear cells had malignancy. From these results, it was suggested that the clear cell (outer cell) played a major role in proliferation and in the potency of malignancy, although epithelialmyoepithelial carcinoma was defined as a low malignant cancer showing a two-cell pattern.