Abstract
Contact endoscopy is a noninvasive tool that allows in vivo and in situ examination of superficial mucosa. Its use for early diagnosis of cancerous lesions of the larynx has not been evaluated very well. In the present study, comparison of contact endoscopy with paraffin section histopathology was performed in 12 patients with laryngeal tumor and 2 patients with vocal fold polyp.
The result showed that contact endoscopy provides information on microscopic diagnosis and laryngeal lesion margins, and enables visualization of the laryngeal mucosa microvasculature. Also, the contact endoscopic findings of superficial cells of the mucosa stained with methylene blue were accurate compared to the paraffin section histopathology, except the tumor with hyperkeratosis.
