EFFICACY OF DEXAMETHASONE CIPECILATE NASAL SPRAY IN THE EARLY TREATMENT OF SEASONAL ALLERGIC RHINITIS

Abstract

We investigated the efficacy of dexamethasone cipecilate nasal spray in the early treatment of seasonal allergic rhinitis (Japanese cedar pollinosis). Dexamethasone cipecilate 400 μg delivered with a specific intranasal spraying device was administered once daily to allergic rhinitis patients visiting the hospital just prior to the cedar pollen season (early treatment group) or after cedar pollen dispersal (late treatment group), and the nasal symptoms and QOL score were compared between the early treatment group with late early treatment group. The nasal symptom score and QOL score at the peak of pollen dispersal were lower in the early treatment group than those in the late treatment group, and we found that the nasal symptoms of the early treatment group were suppressed by dexamethasone cipecilate nasal spray. These results suggest that early treatment with dexamethasone cipecilate nasal spray is effective for reducing the nasal symptoms of seasonal allergic rhinitis.