OK-432 INFUSION THERAPY IN OUR COURSE

Abstract

　OK-432 is an antineoplastic drug, and it has been reported that in infants with lymphangioma, local infusion of the drug yields surgery-like effects. Herein, I report on the clinical outcomes of 12 patients of nead and neck cyst-related diseases who received OK-432 local infusion therapy at our institution between December 2013 and October 2015. The patient comprised 3 men and 9 women, ranging in age from 5 to 60 years old; there were eight cases of ranula, one cases of auricular hematoma, One case of parotid gland cyst, one case of lower lip cyst, and one case of a cyst on the side of the neck. In all cases, except the case with the cyst on the side of the neck, the lesion either reduced in size or altogether disappeared. Our results comfirm local infusion thrapy with OK-432 as an easy, minimally invasive and effective treatment for simple cystic diseases of the head and neck.