Abstract
Trilafon (perphenazine) was administered orally to 12 cases that complained of tinnitis associated with nerve deafness and/or dizziness.
The cases consisted of 7 with Meniere's disease, 1 with atypical Meniere's disease, 2 with senile deafness, 1 with occupational senile deafness and 1 with mixed deafness who complained chiefly of tinnitus. Dizziness was present in 8 and tinnitus in 11 of the cases.
Following treatment with Trilafon, dizziness disappeared in all 8 cases, tinnitus disappeared in 2 and was improved in 7. Although tinnitus did not completely disappear in the majority of the cases, they reported that ringing in their ears was decreased in intensity. The functional state of the autonomic nerves was studied in 7 of the 12 cases with the Imidalin in tracutaneous test and the results were compared with the therapeutic results with Trilafon.
In each case blood pressure readings, total serum cholesterol determinations and anemia studies were carried out.
In summary, it appeared that the action of the drug in relieving tinnitus was slightly inferior to that against dizziness.
