Abstract
For the past few years, the oral treatments of chronic sinusitis have been actively performed. Most of these oral drugs, however, are composed of proteolytic ferments, and so called “non-specific anti-inflammatory drugs ” have not been used yet on this disease.
The author attempted, therefore, to use Indomethacin, a non-steroidal anti-inflammatory drug, for the treatment of 20 patients with chronic sinusitis.
As the result, the author had an impression that Indomethacin seems to be somewhat inferior to proteolytic ferment-drugs, but Indomethacin was effective on chronic sinusitis subjectively and objectively.
Thus, the study on this drug should be continued for further clarification on the actions of Indomethacin.
Also, the author discussed the mechanism of action on the effect of Indomethacin from the Medical viewpoint on inflammation.
