Abstract
Since allergy, hypofunction of the adrenal gland, malnutrition, disturbance in metabolism are among those which may be responsible for the development of nasal or sinus infection in children the effectiveness of Cephranthin in nasal diseases among children was studied. Forty patients aged five to twelve were examined after injections of Cepharanthin, 6 to 9 mg. depending on the weight, for a period of one week.
Then the patients were divided into two groups: one group of children who showed improvement of the symptoms objectively in one week and the other group that did not.
Cepharanthin injection was continued for the former group, while the latter group was treated with a combination of Cepharanthin and other drugs.
Evaluation of the 40 cases after one week's injection with Cepharanthin revealed improvement in 50% of the cases.
Overall effect at the conclusion of the treatment revealed an improvement of the symptoms in 92% of the cases.
Alleviation of swollen turbinates and decrease in discharge were also noticed in many cases.
A long-period administration that extended to 12 weeks did not produced any significant. side-effect.
