Abstract
Histaglobin was administrated to 13 cases of nasal allergy. In all the cases, blood tests, cytological test of the nasal discharge and provocative test of the nasal mucosa were performed.
Our treatment schedule consisted of 1 vial of Histaglobin injected subcutaneously once a week, for 3 weeks, which was counted a one course. One or two courses of treatment were given.
Of the 13 cases, the results in 3 cases were indefinite, but 10 cases showed an improvement in the symptoms and intranasal findings, and favorable effects were observed.
Of the improved 10 cases however, relapse occurred in 3 cases, and provocative tests of the nasal mucosa revealed that the antigen was house-dust in 1 case, hogweed (Ambrosia artemisiaefolia) pollen in 1 case and of unknown origin in the rest.
It is generally believed that the combined use of Histaglobin and ACTH may weaken the effect of the former. But in our 2 effective cases administration of ACTH with a nebulizer did not inhibit the effect of Histaglobin presumably because of its topical application. Moreover, there was another case where the combined use of another anti-allergic agent produced favorable effect.
It was observed that the therapeutic effect of Histaglobin began to appear after injecting 2 to 3 vials of the drug.
