A DOUBLE BLIND TEST ON THE EFFICACY OF ISOPROTERENOL FOR THE CONTROL OF VERTIGO
1973 Volume 16 Issue 5 Pages 599-605
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1973 Volume 16 Issue 5 Pages 599-605
Isoproterenol has a potent dilating effect on the peripheral blood vessels.
A total of 45 patient with vertigo were treated by three different methods with isoproterenol; in the first group by a combination of isoproterenol hydrochloride (10mg) and pronase 3.75mg (KIP-01); in the second group, isoproterenol hydrochloride only (10mg) (KIP-02) and in the third group by pronase (3.75 mg) (KIP-03).
Improvement of subjective symptoms was seen in 86.7% in the first group, 66.7% in the second group and 53.3% in the third group.
Objective improvement of the findings was seen in 73.3% in the first group, 66.7% in the second group and 20.0% in the third group.
The results were tested statistically by x2 test, which showed no significant difference in alleviation of subjective symptoms but significant difference was demonstrated between the first group and the third group (1%), between the second group and the third group (5%) while no significant difference was seen between the first group and the second group.
The results indicate that isoproterenol has beneficial effect on the control of vertigo.
