Abstract
Chordoma is a benign tumor which rarely occurs in the nose and paranasal sinuses. The authors report a case of chordoma that originated in the right maxillary bone with subsequent extension to the hard palate, nasal septum and finally to the left maxillary sinus, ethmoid sinus and the orbit during a 17-year course of repeated recurrence.
In the early stage the tumor showed moderate anisocytosis without atypical cells however, in the late stage the neuclei showed a tendency toward pleomorphic and hyperchromatic changes without malignant characteristics.
Repeated surgical resections of the tumor were encountered by subsequent recurrence. 5 FU and Bleomycin were totally ineffective for the lesion.
The authors conclude that a complete removal of the tumor including the normal surrounding tissues in the early stage would be the rule of treatment of the tumor since this type of tumor could change into sarcoma in the extended course of the lesion.
