Abstract
We examined the preventive efficacy of Cynaclin against pollinosis with the aid of the disk containing cedar pollen extract.
“Cynaclin” nasal drip was sprayed twice a day-two insufflations for each nostril each time. A total of three exposure tests using a disk of a given concentration were administered to one subject at one-week intervals. The efficacy was judged from the delayed onset and the reduced amount of nasal discharge. We explained our results in numbers ranging between 0 and 30, which led to the numerical realization of the preventive efficacy against pollinosis. We named our preventive Tsubaki method after the family name of one of the authors. We treated 25 cases, 20 of whom (80 percent) showed efficacy. Moreover, the reduction of sneezing and itching being taken into consideration, 90 percent of the subjects were relieved from pollinosis. We concluded that Cynaclin was clinically successful in preventing pollinosis.