Abstract
We clinically studied nebulizer therapy as a topical nasal antimicrobial therapy with cefmenoxime hydrochloride for acute rhinosinusitis in children. We evaluated results with the standard for the new antibiotics of the Japanese Society of Chemotherapy. Subjects were 54 children with acute rhinosinusitis. Bacteriological effectiveness was significantly higher in 12 of 25 children (48%) in the group with nebulizer therapy than in 3 of 12 children (25%) in the group without nebulizer therapy. By the standard of total evaluation, consisting of clinical and bacteriological study, the cure rate was very high in 17 of 25 children (68%) given poor cure rate of acute rhinosinusitis in children. We thus found nebulizer therapy with cefmenoxime hydrochloriide to be effective in pediatric acute rhinosinusitis.
