Abstract
Recently, a considerable number of literatures are available as regards enzyme therapy for chronic sinusitis attracting concerns from many clinicians.
The author, discussed several problems of enzyme therapy in which more room remains to be solved.
In present paper, general outline has been given as regards historical background, literatures and mechanism of action of various enzymes for chronic sinusitis.
Fundamental and clinical problems of newly introduced enzymes have also been discussed from author's point of view.
