Abstract
Case 1 is a patient with chronic otitis media and continuous otorrhea. When stapes was manipulated through the space of posterior tympanotomy, stapes was accidentally pulled out and fallen medially. Sensorineural hearing loss and vertigo did not occur fortunately, and hearing was restored by the second surgery. Case 2 is a patient with cholesterin granulaoma. After granulation around the stapes was removed through the space of posterior tympanotomy as much as possible, postoperative sensorineural hearing loss and vertigo occurred, suggesting that inflammation of the inner ear might occur through a microfistula of the stapes footplate. Case 3 is a patient with anaphylaxis shock after i.v. administration of vancomycin (VCN). The rare possibilities that red neck syndrome is induced by release of histamine and that anaphylactic reaction is induced by interaction of VCM and anesthetic drugs such as thiopental were written in drug information notes.