Abstract
We report 2 cases of Otitis Media with ANCA-Associated Vasculitis (OMAAV). Case 1 was a 36-year-old man who presented bilateral otorrhea and vertigo with serum PR3-ANCA positive. He had bilateral mixed hearing loss. Ear symptoms were reduced by the treatment with prednisolone and cyclophosphamide. However, pachymeningitis was complicated subsequentlyand relieved by treatment. Case 2 was a 64-year-old woman who presented bilateral otorrhea and bilateral hearing loss without serum ANCA positive. She had bilateral mixed hearing loss. Ear symptoms were reduced by the treatment with prednisolone and cyclophosphamide. However, pachymeningitis was complicated subsequently, and she had a definitediagnosisof granulomatosis with polyangitisby open biopsy of the pachymeningitis. Pachymeningitis relieved by treatment. In OMAAV, pachymeningitis and neuropathy were easy to be complicated than an ANCA associated vasculitis without otitis media.
