2020 Volume 30 Issue 4 Pages 271-280
Cogan syndrome is a rare disease characterized by non-syphilitic keratitis, vestibular dysfunction, and sensorineural hearing loss. It is a type of vasculitis syndrome and is considered to have an autoimmune origin. Moreover, systemic vasculitis complicates approximately 10%–20% of cases. We report a case of Cogan syndrome in a patient undergoing treatment for eosinophilic otitis media.
A 64-year-old woman, diagnosed with bronchial asthma in her 20s, was dependent on prednisolone (PSL) therapy ever since. Mepolizumab treatment was also started at the age of 62 years.
At the age of 50 years, she was diagnosed with eosinophilic otitis media and was subsequently referred to our department at the age of 62 years. Despite the absence of otorrhea during the course of the disease, the bone conduction threshold persistently increased, and despite PSL administration, her hearing loss progressed. She developed scleritis at the age of 63 years and was treated for this condition at another hospital.
Because there was a notable time lapse between the development of the inner ear disorder and the onset of ocular symptoms, a diagnosis of atypical Cogan syndrome was made. The clinical course of this case was documented, and the relationship between Cogan syndrome and vasculitis was examined.
