Histopathological Studies of the Temporal Bones in Two Cases with DIC

Abstract

The histopathological findings of the temporal bones from two cases with DIC were described. Although hemorrhage in the inner ear was found in the both cases, otological findings were different between the two. Case 1 was a 19-year-old woman with angiosarcoma of the mammary gland. Hemorrhage was observed in the mesotympanum, as well as in the scala tympani and spiral ligament of the basal turn of the cochlea. Tumor cell infiltration was observed in various sites of the middle ear such as around the facial nerve. She, however, had no otological complaint except for slight dizziness. Case 2 was a 46-year-old man with acute myelofibrosis. Severe hemorrhage was observed in the internal auditory canal, the cochlear duct and the saccule. The organ of Corti showed extensive degenration. He had complained of bilateral deafness.