Abstract
Kanamycin was injected to three-day-old chicks at a dose of 200mg/kg. for 10 days and their cochleae were processed for scanning electron microscopy at various times following the last injection. Both hair cells and supporting cells were damaged by kanamycin in the basal 35-40% of the basilar papilla. By 14 days posttreatment, most of the damaged region was replaced with regenerating hair cells and supporting cells. The base-to-apex gradient of morphological development along the longitudinal axis of the cochlea was observed in the course of regeneration. Kinocilium and microvilli were recognized on the apical surface of the regenerating hair cells.
