Abstract
To determine the effect of killed nontypeable H. influenzae on the ciliary activity of the middle ear mucosa, two experimental groups and control group are designed (Group A, saline inoculation into the middle ear; Group B, killed H. influenzae inoculation; Group C, three subcutaneous injection of H. influenzae with Freund's complete adjuvant before inoculation of it into the middle ear). The ciliary movements are analyzed by photo-electric method. Ciliary movements are suppressed by inoculation of killed H. influenzae inoculation in both group B and group C. Suppression of the ciliary movement in group C persists longer than group B. Therefore, immuno-logical mechanism may enhance the suppression of ciliary movement induced by endotoxin of H. influenzae.
