1991 Volume 1 Issue 2 Pages 59-63
The effect of long-term supplemental administration of Saireito on hearing was investigated in 10 cases of a steroid-responsive sensorineural hearing loss. Saireito (3.0-9.0 g/day) was administered orally for more than 2 years and it was examined whether the dose of prednisolone might be reduced without any significant deterioration of hearing.
By the supplemental administration of Saireito for more than 2 years, the dose of prednisolone was reduced in 8 out of 10 (80.0%) cases. In these 8 cases, the mean dose of 5.5mg/day of prednisolone was reduced without any significant deterioration of hearing. When theresults obtained in this study were compared with our previous data, it was suggested that the longer the term of supplemental administration of Saireito, the larger the reduction of dose of prednisolone without any significant deterioration of hearing.
It was concluded that the long-term supplemental administration of Saireito is very useful in order to reduce the large dose of prednisolone without any significant deterioration of hearing in a steroid-responsive sensorineural hearing loss.
