Abstract
Post-lesional plasticity following unilateral labyrinthectomy is considered as an excellent model of plasticityof the adult central nervous system. Indeed, the static and dynamic postural and oculomotor syndromesobserved at the acute stage largely disappear over time in all species of vertebrates that have been studied.First, we have briefly summarized the studies of our group, which have used electrophysiological and moleculartechniques together with morphological methods to investigate the neuronal basis of vestibular compensation.Second, the main characteristics of the compensation process in vestibular patients were summarized.An attempt was made to link the findings of various clinical studies on that topicwith the results of previousinvestigations in animal models. Such a comparison may open new directions for clinical research on vestibulartests and vestibular syndromes and could suggest new pathways of investigation for vestibular rehabilitation.
