Single-molecular mechanics of biomolecular motors

Abstract

The progress in optical microscopy has made it possible to observe the behavior of single biomolecules in real time, and even to quantitatively measure the movement of an order of nm and the force generation of an order of pN. Here, we introduce one aspect of the studies on the single-molecular mechanics of molecular motors, i. e. , myosin (II, V) and kinesin, which interact with an actin filament and a microtubule, respectively.