2011 Volume 80 Issue 2 Pages 120-123
It has been reported that the combined treatment with radiation and anti-cancer agents including platinum is useful for the anti-cancer treatment, because of the platinum absorbing the X-ray and releasing the secondary electron. However, the platinum can absorbe only the X-ray with the specific energy, whereas the X-ray used in clinical medicine has the white spectroscopy. And then, the dose of anti-cancer agents is limited due to the unpleasant effects. We try to make the novel chemoradiation treatment system with high specificity and high cytotoxicity, replacing the white X-ray to the monochromatic X-ray, and using the active targeting drug delivery system to increase the platinum concentration in cancer tissue.